The official YouTube channel for the three-member Japanese rock band Mrs. GREEN APPLE has started streaming a music video for their latest digital single song “Kusushiki,” which has been featured as the second opening theme for the ongoing The Apothecary Diaries Season 2 TV anime. The video is set in a fictional world with no time period or nationality setting, and is depicted entirely in full CG.
Mrs. GREEN APPLE “Kusushiki” Music Video
The Apothecary Diaries Season 2 Creditless 2nd Opening Video
As Mrs. GREEN APPLE’s 16th digital single, “Kusushiki” released on April 5.

“Kusushiki” digital single jacket
The first season of the TV anime adaptation of The Apothecary Diaries aired for 24 episodes from October 2023 to March 2024. The second season premiered in Japan on January 10, 2025, and is simulcast on Crunchyroll for members in North America, Central America, South America, Europe, Africa, Oceania, the Middle East and CIS.
Crunchyroll describes the series:
Maomao lived a peaceful life with her apothecary father. Until one day, she’s sold as a lowly servant to the emperor’s palace. But she wasn’t meant for a compliant life among royalty. So when imperial heirs fall ill, she decides to step in and find a cure! This catches the eye of Jinshi, a handsome palace official who promotes her. Now, she’s making a name for herself solving medical mysteries!